Depo-Provera Lawsuit
Have You Experienced Adverse Effects from Depo-Provera?
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​Depo-Provera has been used by hundreds of thousands of women across the country, yet for many, this once-trusted contraceptive’s promise of convenience turned into a nightmare of severe health problems.
Now, these women are fighting back in court. Lawsuits nationwide allege that Pfizer, Depo-Provera’s manufacturer, put profits before patient safety by failing to warn about life-altering side effects like dangerous brain tumors and irreversible bone loss. If you or a loved one was harmed by this dangerous drug, you have the right to seek justice and substantial compensation for your suffering.
Our experienced legal team is ready to stand with you to hold Pfizer accountable because no company should get away with putting profits over patient safety.
What Is Depo-Provera?
Depo-Provera is a prescription birth control injection containing medroxyprogesterone acetate, a synthetic form of the hormone progestin. Approved by the FDA in 1992, it is administered every three months and has become popular for its convenience and long-term effectiveness.
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However, recent medical studies have linked long-term use of Depo-Provera to a heightened risk of developing intracranial meningioma brain tumors — slow-growing tumors that can lead to serious neurological harm, including cognitive decline, vision or hearing loss, and the need for invasive brain surgery.
These findings have sparked a wave of lawsuits against Pfizer Inc., the drug’s manufacturer, with plaintiffs alleging that Pfizer failed to warn U.S. patients and healthcare providers about these risks, despite updating warnings in Europe.​
Common Health Risks Reported by Plaintiffs
Allegations Include:
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Meningioma Brain Tumors: Long-term use of Depo-Provera has been linked to the development of intracranial meningiomas — non-cancerous brain tumors that can lead to serious neurological complications, including permanent cognitive impairment and the need for invasive brain surgery.
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Neurological Damage: Plaintiffs report vision problems, hearing loss, memory issues, and neurological symptoms caused by the growth of meningioma tumors pressing on critical areas of the brain.
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Permanent Health Risks: Many women have faced lifelong medical consequences following meningioma diagnoses, including repeated surgeries, radiation treatments, and long-term cognitive or neurological decline.
Plaintiffs allege that Pfizer failed to update Depo-Provera’s U.S. warning labels to reflect the severe and permanent risk of brain tumors, despite adding such warnings in Europe. They claim Pfizer downplayed or ignored emerging scientific evidence of this serious risk.
Recent Legal Developments in 2025
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As of 2025, Depo-Provera lawsuits have been consolidated into Multidistrict Litigation (MDL No. 3140), centralized in the Northern District of Florida. This MDL allows hundreds of similar cases to be managed efficiently in one federal court, streamlining pre-trial proceedings such as discovery, expert testimony, and motions. While no settlements have been finalized, MDLs often serve as a pathway toward large-scale resolutions once bellwether trials begin.
Notable Updates on the Depo-Provera MDL (July 2025)
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The MDL is now centered on claims of intracranial meningioma brain tumors caused by long-term Depo-Provera use.
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Expert witnesses have presented scientific studies linking Depo-Provera’s active ingredient (medroxyprogesterone acetate) to a significantly increased risk of brain tumors after prolonged exposure.
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Plaintiffs include women of all ages — from younger adults to postmenopausal women — who received multiple injections over the years and later developed meningiomas requiring surgery, radiation, or ongoing neurological care.
Who Is Eligible to File a Depo-Provera Brain Tumor Lawsuit?
You may qualify for a Depo-Provera lawsuit if you:
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Received Depo-Provera injections consistently for over a year
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Were diagnosed with an intracranial meningioma (brain tumor)
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Experienced neurological complications (vision issues, hearing loss, memory problems, cognitive decline)
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Were never warned about the risk of brain tumors by your healthcare provider
Evidence You’ll Need to Support Your Claim:
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Medical records confirming Depo-Provera injections
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Diagnostic imaging confirming meningioma diagnosis (MRI, CT scans)
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Treatment records (surgeries, radiation, ongoing neurological care)
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Personal notes or journals tracking symptoms and medical impacts
How to File a Depo-Provera Lawsuit:
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Consult a Product Liability Attorney: Work with a lawyer experienced in pharmaceutical litigation and mass tort cases involving brain injuries.
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Preserve Medical Records: Secure complete records of your Depo-Provera injections, diagnosis, and treatments.
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Document Your Symptoms: Keep detailed notes about any physical, cognitive, or emotional changes you’ve experienced.
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Act Within the Statute of Limitations: Deadlines vary by state, typically 2–3 years from diagnosis or discovery of harm.
What Compensation May Be Available?
Victims of Depo-Provera-related meningioma brain tumors may be entitled to compensation for:
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Medical Expenses: Current and future treatment costs for surgeries, therapies, and long-term care
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Pain and Suffering: Physical pain, emotional distress, loss of quality of life
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Lost Wages: Compensation for missed work or reduced earning potential
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Punitive Damages: If the court finds Pfizer acted recklessly or failed to warn consumers appropriately
What Could a Settlement Look Like?
While no national settlement has been finalized, legal analysts estimate potential individual payouts for qualified cases could range from $275,000 to $500,000 or more, depending on:
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Tumor severity
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Long-term medical needs
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Proof of Depo-Provera use
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Impact on your life and livelihood
​​​​​​Health Guidance and Next Steps
If you've used Depo-Provera:
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Talk to a doctor about alternative contraception options
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Reach out to a licensed attorney to explore your legal rights
​References & Author
Last Updated: July 2025
Author: Legal Writers & Researchers at The Spencer Law Firm
Health Guidance and Next Steps
FAQ
Frequently Asked Questions (FAQ)
Q: What is the Depo-Provera lawsuit about?
A: The lawsuit claims that Pfizer failed to warn patients about the increased risk of meningioma brain tumors from long-term Depo-Provera use.
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Q: Is Depo-Provera still on the market in 2025?Yes, it's still A: FDA-approved, but now includes stronger warnings on prolonged use and bone health monitoring.
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Q: What is meningioma?
A: Meningioma is a tumor that forms in the lining of the brain. It can cause serious neurological symptoms and may require surgery or radiation.
Q: Do I have to be currently experiencing symptoms to file?
A: No. If you've been diagnosed with a brain tumor and used Depo-Provera long term, you may still qualify—even if your symptoms have stabilized.
Q: Is there a time limit to file a claim?
A: Yes. Most states have a 2–3 year statute of limitations from the date you discovered (or should have discovered) the injury. Don't delay.
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Q: Can I sue even if I stopped using Depo-Provera years ago?
A: Possibly. The timeline starts from when you became aware of the injury, not your last injection—check your state’s statute of limitations.
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Q: How long do these lawsuits take?
A: MDL cases often take 1–3 years. Early bellwether trials may shape future settlement talks.
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Q: How much does it cost to file?
A: Most law firms — including ours — work on a contingency basis, meaning you pay nothing unless we win compensation for you.
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Q: Do I need to pay upfront to file a lawsuit?
A: Most product liability attorneys work on a contingency fee basis, meaning you pay nothing unless they win your case.
